Key result
Emergency non-cardiac surgery in elderly patients is linked to ~5-fold higher mortality than elective procedures.
Why the study?
Elderly patients undergoing emergency non-cardiac surgery have a significantly higher mortality rate, motivating the need for reliable preoperative prediction of myocardial injury after non-cardiac surgery (MINS).
Can a risk prediction model incorporating polypharmacotherapy reliably predict myocardial injury after emergency non-cardiac surgery in elderly patients?
Can a risk prediction model incorporating polypharmacotherapy reliably predict myocardial injury after emergency non-cardiac surgery in elderly patients?
This review explores preoperative risk prediction models, emphasizing the role of polypharmacotherapy, for assessing myocardial injury after non-cardiac surgery in elderly patients.
Higher mortality in elderly emergency non-cardiac surgery warrants vigilance; leaves open reliable preoperative MINS prediction.
Many studies conducted in the field of cardiology have recently shown that elderly patients (≥ 65 years old) who undergo emergency non-cardiac surgery have a significantly higher mortality rate (12.5%) compared to patients who undergo elective surgery (2.6%). In this regard, many doctors are wondering whether it is possible to reliably predict myocardial injury after non-cardiac surgery (MINS) at the preoperative stage. The search was conducted in January–September 2025 using the PubMed, Scopus, and Web of Science databases. Publications from 2005 to 2025 were considered. The review included original articles, meta-analyses, and systematic analyses relevant to the selected topic.
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Shimanovskiy et al. (2026) conducted a review in Myocardial injury after non-cardiac surgery (MINS). Polypharmacotherapy and risk prediction models was evaluated. Elderly patients (≥ 65 years old) undergoing emergency non-cardiac surgery have a significantly higher mortality rate (12.5%) compared to those undergoing elective surgery (2.6%).
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