Key result
Type 2 diabetes linked to ~1.6 mmol/L higher total cholesterol versus healthy controls.
Why the study?
Little is known about the lipid profile pattern and prevalence of dyslipidemia among Ghanaian patients with type 2 diabetes mellitus.
Cross-Sectional (n=161)
No
Answers are grounded in this paper and cite their sources.
Supports lipid screening in type 2 diabetes; extends cross-sectional data but leaves open longitudinal outcome prediction.
OBJECTIVE: This study aimed to evaluate dyslipidemia in Ghanaian subjects with type 2 diabetes. RESULTS: Hundred individuals with type 2 diabetes and 61 apparently healthy controls participated. The prevalence of hypercholesterolemia among persons with type 2 diabetes was 53%. Blood pressure, fasting blood glucose (FBG), triglyceride (TG), low-density lipoproteins (LDL) and alanine transaminase (ALT) levels were higher in persons with type 2 diabetes compared with the control group (p < 0.01). Positive correlations were found within persons with type 2 diabetes for triglyceride vs FBG; ALT vs age and aspartate transaminase (AST) vs TG (p < 0.05 respectively). This study demonstrated hyperlipidemia and poor liver health in persons with type 2 diabetes.
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Ofori et al. (2019) conducted a cross-sectional in Type 2 diabetes (n=161). Type 2 diabetes vs. Healthy controls was evaluated on Total cholesterol (mmol/L) (95% CI -1.76 to -1.33, p=<0.0001). Patients with type 2 diabetes exhibited significantly higher total cholesterol levels (6.13 vs 4.58 mmol/L) and a 53% prevalence of hypercholesterolemia compared to healthy controls.
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