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May 1, 2008

Type 2 diabetes was associated with marked hypertriglyceridaemia and a significantly raised TG/HDL ratio in females (P<0.05) compared to non-diabetic controls.

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Population

160 subjects, including 83 known type 2 diabetics and 77 age-matched controls

Design

Cross-sectional

Key result

Type 2 diabetes was associated with marked hypertriglyceridaemia and a significantly raised TG/HDL ratio in females (P<0.05) compared to non-diabetic controls.

Authors

SKSanober KhanNANishat AyubSNSohail Nawab

Discussion

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Overview

May flag dyslipidemia risk in diabetic women; hypothesis-generating for CHD prediction pending prospective data.

Study Design

Type

Observational (n=160)

Multicenter

No

Structured PICO

P
Population
160 subjects, including 83 known type 2 diabetics and 77 age-matched controls, evaluated for serum lipid profiles.
C
Comparator
77 age-matched non-diabetic controls
O
Outcome
Ratios of serum triglycerides and cholesterol levels (TG/HDL ratio, LDL/HDL ratio)surrogate

Main Result

p-value: p=<0.05

Type 2 diabetes is associated with marked hypertriglyceridemia and an elevated TG/HDL ratio, particularly in females, which may serve as a marker for dyslipidemia and coronary heart disease risk.

Cite This Study

Khan et al. (2008) conducted an observational in Type 2 diabetes mellitus (n=160). Type 2 diabetes mellitus vs. Age-matched non-diabetic controls was evaluated on TG/HDL ratio (p=<0.05). Type 2 diabetes was associated with marked hypertriglyceridaemia and a significantly raised TG/HDL ratio in females (P<0.05) compared to non-diabetic controls.

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Serum Triglyceride and TG/HDL-Cholesterol Ratio in Good and Poor Control Type-2 Diabetes Mellitus2024
  2. 2Evaluation of dyslipidemia in type 2 diabetes mellitus2015 · 10 citations
  3. 3Frequency and pattern of dyslipidemia in diabetes mellitus type 2.2021 · 2 citations
  4. 4Lipid profile of type 2 diabetic patients at a rural tertiary hospital in Nigeria2010 · 13 citations
  5. 5Plasma Lipid Levels at Diagnosis in Type 2 Diabetic Patients1993 · 8 citations