Challenges in Vaccination of Patients with Transfusion-dependent Thalassemia

catch-up vaccination program, forcing families to incur out-of-pocket costs.To combat these barriers and reduce "missed opportunities," clinicians should advocate for integrating vaccination services directly into routine day-care transfusion visits.This strategy simultaneously improves adherence and leverages existing clinical touchpoints to ensure comprehensive care for this vulnerable population.In conclusion, vaccination in TDT patients is essential yet challenging.Strengthening vaccination delivery through standardized protocols, serologic monitoring, and integration into transfusion services may substantially reduce preventable infectious morbidity in TDT.A tailored approach and adherence to updated guidelines are the need of the hour.