Key result
Minoxidil-associated pericardial effusion resolves despite continuing therapy in a documented case.
Why the study?
Pericardial effusions associated with minoxidil therapy are rare and usually linked to severe renal or congestive heart failure, but can occur without identifiable cause.
Case Report (n=1)
Isolated minoxidil-related effusion without heart failure is rare and may resolve on continued therapy; leaves open causality and monitoring needs.
• Pericardial effusions are occasionally observed in patients treated with the new oral vasodilator, minoxidil. Almost all of these cases are related to severe renal or congestive heart failure, but very rarely can be observed in patients without an identifiable cause. Such a case is reported herein, in which extensive investigation failed to reveal the cause. On further observation, the effusion subsided despite continuation of minoxidil therapy. Review of the literature suggests that pericardial effusion is uncommonly observed in patients treated with minoxidil unless accompanied by renal or cardiac failure, and that discontinuation of minoxidil therapy is not always indicated. (Arch Intern Med141:69-71, 1981)
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Mark C. Houston (1981) conducted a case report in Pericardial effusion (n=1). Minoxidil therapy was evaluated. Pericardial effusion associated with minoxidil therapy subsided despite continuation of the medication in a patient without an identifiable cause.
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