Key result
Low-dose oral minoxidil triggers recurrent pericardial effusion and pericarditis in a healthy patient.
Why the study?
Minoxidil-related pericarditis with rapid onset of pericardial effusion has not been previously documented in patients without kidney or heart failure history.
Case Report (n=1)
No
Highlights that short-term, low-dose minoxidil use can induce rapid-onset pericarditis and pericardial effusions even in individuals without preexisting heart or kidney disease.
May link low-dose minoxidil to rapid pericarditis/effusions without comorbidities; extends prior reports but remains hypothesis-generating.
This paper reports a case of a 53-year-old man presenting with recurrent pericardial effusions and one episode of pericarditis after short-term, low-dose minoxidil use, without prior kidney or heart failure history. The uniqueness lies in the rapid onset of a moderate pericardial effusion within 20 days, notably shorter than previously documented.
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Abdulhai et al. (2024) conducted a case report in Minoxidil-related pericarditis and pericardial effusion (n=1). Minoxidil was evaluated on Development and resolution of pericardial effusion and pericarditis. Low-dose minoxidil exposure resulted in the rapid onset of recurrent pericardial effusions and pericarditis in a patient without prior heart or kidney disease.
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