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Adrenal endothelial cysts are rare lesions that may present as large retroperitoneal masses and mimic other cystic adrenal or retroperitoneal tumors. We report a 54-year-old man with progressive left lumbar pain caused by a giant left retroperitoneal cystic mass measuring 19.2 × 18.1 × 12.0 cm, displacing adjacent organs. Open surgical excision was performed after controlled intraoperative decompression. Histopathology showed a fibrous cyst wall lined by bland flattened CD34-positive endothelium with residual adrenal tissue, confirming an adrenal endothelial cyst. Surgery provided definitive diagnosis and treatment with an uneventful postoperative course.
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Hajri et al. (2026) studied this question.
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