Key result
Study protocol outlines background and clinical trial objectives without reporting results.
Why the study?
Current sodium intake guidelines recommend less than 2,300 mg/day for healthy adults to reduce cardiovascular risk, but the relation between sodium, blood pressure, and vascular function varies with energy intake, complicating a single absolute sodium recommendation.
Absolute sodium targets may need energy-adjusted personalization in practice; protocol leaves open effects on BP and endothelial outcomes.
Objectives: Current guidelines recommend healthy adults consume < 2,300 mg sodium/day to mitigate cardiovascular (CVD) risk. Sodium intake is strongly positively correlated with calorie intake, making it challenging for some to achieve sodium recommendations. Additionally, the strength of the relation between sodium intake and both blood pressure and vascular endothelial function varies with energy intake. Setting one absolute sodium intake recommendation without consideration for energy may be impractical.
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Lobene et al. (2026) studied this question. Sodium reduction strategies was evaluated. As a study protocol, the abstract provides background objectives but reports no results or main findings.
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