Preoperative administration of CIPLA®: Experience of the thoracic surgery clinic, University Clinical Center of the Republic of Srpska

This is the authors' abstract. We don't add key points for this paper.

Introduction: Lung cancer is often associated with chronic obstructive pulmonary disease (COPD), which significantly increases perioperative risk. Preoperative optimization of pulmonary function is an important step in preparing patients for anatomical lung resections. Methods: In this prospective analysis, patients (total n=40) were divided in to two groups: a control group (n=20) and an interventional group (n=20) that received CIPLA® inhalation therapy for three days prior to surgery. Spirometry was performed in all patients at three time points: preoperatively, immediately before the procedure, and one month after surgery. In addition to functional parameters, postoperative complications and length of hospitalization were monitored. Results: Patients in the CIPLA® group demonstrated stabilization and improvement of spirometric values compared to expected ppo values, with no postoperative complications observed. The length of hospitalization was shorter (1-4 days) compared to the control group, where the average stay was longer. Conclusion: Preoperative administration of CIPLA® inhalation therapy showed a positive effect on pulmonary function and postoperative course in patients with lung cancer. Although our data are based on a limited sample, they suggest that CIPLA® inhalations represent a reliable and practical solution for optimizing patients with chronic respiratory conditions.