Key result
Implementation science-based weight management reduces BMI by ~2 points in obese HFpEF patients.
Why the study?
There was a need to construct and evaluate an evidence-based weight management program based on implementation science theory for obese HFpEF patients.
Does an evidence-based weight management program guided by implementation science improve body weight, exercise tolerance, and quality of life in obese patients with HFpEF?
RCT (n=186)
Random number table method
No
Does an evidence-based weight management program guided by implementation science improve body weight, exercise tolerance, and quality of life in obese patients with HFpEF?
Absolute Event Rate: 32.1% vs 34.2%
p-value: p=<0.001
A structured, evidence-based weight management program developed using implementation science frameworks significantly improved weight reduction, functional capacity, and quality of life in obese patients with HFpEF compared to standard care.
Supports integration of implementation science-guided weight management into obese HFpEF care; extends evidence for targeted lifestyle protocols in this population.
屈 燕 ( 宁夏医科大学总医院 ) 胡好宾 ( 宁夏医科大学总医院 ) 马 平 ( 宁夏医科大学总医院 ) 目的:构建基于实施科学理论的肥胖型射血分数保留心力衰竭(HFpEF)患者体重管理循证方案,并评 估其临床应用效果。方法:选取2022年1月-2025年1月我院收治的186例肥胖型HFpEF患者,随机数字表法分为观察组 和对照组各93例。对照组接受常规护理干预,观察组在常规护理基础上实施基于实施科学理论的体重管理循证方案。 比较两组患者干预前后的体重指数、6分钟步行距离及生活质量评分变化情况。结果:干预后观察组患者的各项指标 改善程度均显著优于对照组(P < 0.05)。结论:基于实施科学理论构建的肥胖型HFpEF患者体重管理循证方案能够 有效改善患者体重控制情况,提高运动耐量和生活质量,为该类患者的临床护理提供了科学依据。 目的:构建基于实施科学理论的肥胖型射血分数保留心力衰竭(HFpEF)患者体重管理循证方案,并评 估其临床应用效果。方法:选取2022年1月-2025年1月我院收治的186例肥胖型HFpEF患者,随机数字表法分为观察组 和对照组各93例。对照组接受常规护理干预,观察组在常规护理基础上实施基于实施科学理论的体重管理循证方案。 比较两组患者干预前后的体重指数、6分钟步行距离及生活质量评分变化情况。结果:干预后观察组患者的各项指标 改善程度均显著优于对照组(P < 0.05)。结论:基于实施科学理论构建的肥胖型HFpEF患者体重管理循证方案能够 有效改善患者体重控制情况,提高运动耐量和生活质量,为该类患者的临床护理提供了科学依据。
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屈 et al. (2026) conducted an RCT in Obese Heart Failure with Preserved Ejection Fraction (n=186). Implementation science-based evidence-based weight management protocol vs. Routine nursing intervention was evaluated on Body Mass Index (BMI, kg/m2) post-intervention (p=<0.001).
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