Key result
Self-rated health dissatisfaction is linked to ~29% higher all-cause mortality after NSTEMI.
Why the study?
The association between subjective health perception and mortality risk in patients with NSTEMI was not well established.
Does poor self-rated health predict all-cause mortality in patients with NSTEMI?
Cohort (n=29,465)
Yes
Does poor self-rated health predict all-cause mortality in patients with NSTEMI?
Hazard Ratio: 1.29 (95% CI 1.16–1.44)
Absolute Event Rate: 58.03% vs 47.11%
p-value: p=<0.001
Poor self-rated health independently predicts increased long-term all-cause mortality in patients with NSTEMI, highlighting its potential value in clinical risk stratification.
Background: This investigation aimed to examine the association between subjective health perception and mortality risk in individuals diagnosed with non-ST-segment elevation myocardial infarction (NSTEMI). Methods: This study conducted a multicenter retrospective analysis of 29,465 patients with NSTEMI from 82 tertiary and secondary hospitals in Tianjin, China (2010–2023). Patients were stratified into self-rated health (SRH)-satisfied (n = 28,835) and SRH-dissatisfied (n = 630) cohorts based on self-reported health assessments. Propensity score matching (1:3 ratio) was used to balance baseline characteristics, yielding a final sample of 2514 patients. The primary outcome was all-cause mortality over a median follow-up of 1477 days. Multivariable Cox regression was used to identify predictors of mortality, and Kaplan-Meier analysis was performed to compare survival between groups. Results: The SRH-dissatisfied cohort exhibited advanced age, reduced percutaneous coronary intervention (PCI) utilization, and greater comorbidity burden (diabetes, hypertension, chronic kidney disease, cerebrovascular/peripheral vascular disease, chronic lung disease; p < 0.05). This group demonstrated significantly elevated mortality (adjusted Hazard Ratio [aHR] = 1.29, 95% confidence interval [CI]: 1.16–1.44; p < 0.001). No between-group differences were observed for secondary endpoints: nonfatal myocardial infarction (MI), cardiac death, ischemic stroke, or revascularization. Subgroup analyses stratified by age, sex, and comorbidity status confirmed the consistency of the results. Conclusions: Self-rated health independently predicts mortality risk in patients with NSTEMI.
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Cao et al. (2026) conducted a cohort in Non-ST-segment elevation myocardial infarction (NSTEMI) (n=29,465). Self-rated health dissatisfaction vs. Self-rated health satisfaction was evaluated on All-cause mortality (aHR 1.29, 95% CI 1.16-1.44, p=<0.001). Self-rated health dissatisfaction independently predicted a significantly higher risk of all-cause mortality (aHR 1.29) compared to self-rated health satisfaction in patients with NSTEMI.
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