Key result
POSSUM predicts 30-day mortality well with AUC ~0.78, but shows limited discrimination for morbidity.
Why the study?
The predictive accuracy of the POSSUM score for 30-day morbidity and mortality after emergency laparotomy was uncertain.
Does the POSSUM scoring system accurately predict 30-day morbidity and mortality in patients undergoing emergency laparotomy?
Cross-Sectional (n=146)
No
Does the POSSUM scoring system accurately predict 30-day morbidity and mortality in patients undergoing emergency laparotomy?
Effect estimate: AUC 0.782 (95% CI 0.692-0.872)
p-value: p=<0.001
The POSSUM scoring system provides satisfactory risk stratification for 30-day mortality but has limited predictive ability for 30-day morbidity following emergency laparotomy.
May aid mortality risk stratification but not morbidity after emergency laparotomy; leaves open broader adoption pending prospective validation.
Objective:To assess the predictive accuracy of the Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM) for the prediction of 30-day morbidity and mortality in patients undergoing emergency laparotomy.Study Design:Prospective cross-sectional study.Place and Duration:This study was carried out at Indus Medical College Tando Muhammad khanPakistan, from April 2025 to April 2026Methods:The study included patients aged 15–75 years who underwent emergency laparotomy, excluding polytrauma and immunocompromising disease, including chronic liver disease, chronic renal failure, COPD, asthma, HIV, malignancy, and genetic diseases. A total of 146 consecutive patients were entered. Demographic and clinical data were obtained, POSS physiological and operative scores were computed, and a 30-day follow-up was conducted to assess morbidity and mortality. Data were summarized by mean ± SD or median and IQR, frequencies were used for qualitative data, and discrimination was assessed using ROC curves.Results:The cohort included 88 males (60.3%), with a mean age of 46.8 ± 14.5 years. The most common indications were perforation peritonitis (42.5%) and intestinal obstruction (31.5%). Thirty-day mortality was 18 patients (12.3%), and morbidity was 72 patients (49.3%). The ROC curve demonstrated satisfactory discrimination for mortality (AUC 0.782, p < 0.001) and moderate prediction for morbidity (AUC 0.618, p = 0.092).Conclusion:POSSUM is a useful predictor of 30-day mortality but not morbidity in the emergency laparotomy population. Although useful for mortality risk stratification, greater sophistication or localization of models is necessary to predict morbidity.
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Ahmed et al. (2026) conducted a cross-sectional in Emergency Laparotomy (n=146). POSSUM scoring system was evaluated on Prediction of 30-day mortality (AUC 0.782, 95% CI 0.692-0.872, p=<0.001). The POSSUM scoring system demonstrated satisfactory discrimination for predicting 30-day mortality (AUC 0.782) but limited predictive ability for 30-day morbidity (AUC 0.618) in patients undergoing emergency laparotomy.
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