Key result
Newly diagnosed type 2 diabetes affects lipid profiles, with dyslipidemia present in ~95% of patients.
Why the study?
The prevalence and pattern of dyslipidemia among patients with newly diagnosed Type II Diabetes Mellitus and its association with clinical and demographic factors were not well characterized.
Cross-Sectional (n=118)
No
A very high prevalence of mixed dyslipidemia (94.9%) was identified among newly diagnosed T2DM patients, underscoring the importance of early lipid screening in this high-risk population.
High dyslipidemia prevalence in new T2DM supports routine lipid screening; leaves open need for prospective outcome studies.
Objective: To determine the prevalence and pattern of dyslipidemia among patients with newly diagnosed Type II Diabetes Mellitus (T2DM) and to evaluate its association with clinical and demographic factors.Methods: This descriptive cross-sectional study was carried out at the Department of Medicine, Liaquat University Hospital, Hyderabad/Jamshoro, in the period of July to December 2025. Newly diagnosed T2DM patients aged 30-70 years were enrolled. T2DM was defined based on standard diagnostic criteria including fasting plasma glucose ≥126 mg/dL and HbA1c ≥6.5%. Dyslipidemia was defined as the presence of at least one abnormal lipid value based on standard cut-offs.Results: Of total 118 patients, the median age was 51.0 years (IQR 40.0–58.0). Dyslipidemia was observed in 112 (94.9%) patients. A significantly higher association of dyslipidemia was observed among males (p-value =0.036), obese patients (p-value =0.004), duration of diabetes ≤5 months (p-value =0.033), those with low or inactive physical activity (p-value <0.001), and those with a positive family history of diabetes (p-value =0.040). Of 112 dyslipidemia patients, the pattern of dyslipidemia revealed that hypercholesterolemia occurred mostfrequently 91 (81.2%), followed by hypertriglyceridemia 68 (60.7%), and low HDL-C 63 (56.2%). Mixed dyslipidemia (≥2 abnormalities) was present in 78 (69.6%) of patients.Conclusion: Most newly diagnosed T2DM patients had dyslipidemia, commonly presenting with mixed lipid abnormalities, and these were significantly associated with male gender, obesity, low activity, short diabetes duration, and family history.
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Ali et al. (2026) conducted a cross-sectional in Newly diagnosed Type II Diabetes Mellitus (n=118). Newly diagnosed Type II Diabetes Mellitus was evaluated on Prevalence of dyslipidemia. Among patients with newly diagnosed Type II diabetes, the prevalence of dyslipidemia was 94.9%, most frequently presenting as hypercholesterolemia (81.2%) or mixed dyslipidemia (69.6%).
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