Key result
Transcatheter mitral prosthesis undergoes late ~5-mm migration, causing paravalvular leak and fatal reoperation.
Why the study?
Transcatheter mitral valve implantation is a technically challenging procedure with specific complications including device malposition or migration, and the impact of prior valve-in-valve TAVI on prosthesis stability is unclear.
Case Report (n=1)
No
This case highlights the rare but serious risk of late atrial migration of transcatheter mitral valves, even in complex anatomical settings where prior prostheses might theoretically enhance stability.
Late TMVI migration warrants extended surveillance; single case leaves open long-term anchoring durability questions.
Transcatheter mitral valve implantation (TMVI) has emerged as a therapeutic option for patients at high surgical risk or with prior valvular interventions.Despite increasing use, the procedure remains technically challenging and associated with specific complications, including left ventricular outflow tract obstruction, device malposition or migration, and paravalvular regurgitation [1,2].Pre-procedural anatomy plays a key role in determining procedural outcomes.The interaction between the anterior mitral leaflet, annular geometry, and the left ventricular outflow tract may significantly influence device expansion, anchoring, and complication risk [3].
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Josef et al. (2026) conducted a case report in Mitral stenosis and aortic bioprosthesis degeneration (n=1). Combined valve-in-valve transcatheter aortic valve implantation and transcatheter mitral valve implantation was evaluated on Device stability and clinical outcome at 1 year.
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