Key result
AF and PVCs on Holter link to severe LV dysfunction, but NSVT does not.
Why the study?
Arrhythmias are common complications in patients with left ventricular systolic dysfunction, but their association with severity and specific arrhythmia types requires clarification.
Cross-Sectional (n=100)
No
In patients with left ventricular systolic dysfunction, 24-hour Holter monitoring frequently detects arrhythmias, with atrial fibrillation and PVCs showing a significant association with greater LVSD severity.
May support arrhythmia monitoring in LV assessment; hypothesis-generating and should not yet change practice.
Background: Heart failure is a clinical syndrome resulting from certain causes, such as ischemic heart disease, diabetes mellitus, hypertension, smoking, thyroid diseases, myocarditis, metabolic syndromes, and others. When heart failure developed, patients were prone to certain complications. One of the most common complications is arrhythmias. Patient and Method: An observational-cross-sectional study at the Ibn- Albitar Cardiothoracic Center from December 2017 until January 2019. One hundred patients above 14 years old with left ventricular systolic dysfunction are included. Twenty-four-hour Holter monitoring for those patients had been applied. Results: Mean age 54.4 years, 78 were males, and 22 were females. All patients studied had EF less than 50%, with fifty-four of them having EF less than 30%, while forty-six patients had EF more than 30%. 54 patients with DCM and 46 patients with ischemic cardiomyopathy. Holter Monitoring revealed 37 patients with NSVT, 28 patients with AF, and 8 patients with PVCs. Conclusion: Atrial fibrillation and PVCs are significantly associated with severe left ventricular systolic dysfunction, in contrast with NSVT, which shows are significantly associated with severe left ventricular systolic dysfunction in contrast with NSVT, where there is no significant association with increasing severity of left ventricular systolic dysfunction. although it is significantly associated with left axis deviation, left bundle branch block, and left ventricular aneurysm.
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Basheer et al. (2026) conducted a cross-sectional in Left ventricular systolic dysfunction (n=100). 24-hour Holter monitoring was evaluated on Arrhythmias (NSVT, AF, and PVCs). 24-hour Holter monitoring revealed that atrial fibrillation and PVCs were significantly associated with severe left ventricular systolic dysfunction, whereas NSVT was not.
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