Key result
Bilateral sagittal split osteotomy triggers intraoperative asystole via the trigeminocardiac reflex.
Why the study?
Episodes of trigeminocardiac reflex causing asystole during mandibular procedures like bilateral sagittal split osteotomy are infrequently reported and not well recognized.
Case Report (n=1)
Manipulation of the mandibular division of the trigeminal nerve during bilateral sagittal split osteotomy can trigger the trigeminocardiac reflex, leading to life-threatening asystole that requires prompt recognition and resuscitation.
Awareness of trigeminocardiac reflex is warranted in orthognathic surgery; extends known triggers but leaves open prospective evaluation.
The trigeminocardiac reflex (TCR) occurs when branches of the trigeminal nerve are stimulated by physical and/or chemical triggers, leading to cardiac changes. It is commonly associated with midface manipulation, especially in the orbital region and similar incidents with mandibular procedures are not frequently reported. A girl in her late teens with no significant medical history or concurrent medications developed asystole during a bilateral sagittal split osteotomy (BSSO) under general anaesthesia. Prompt cardiopulmonary resuscitation led to the return of spontaneous circulation. The surgery was successfully completed post resuscitation.Although uncommon, similar episodes associated with manipulation of the mandibular division of the trigeminal nerve have been reported previously. This case describes a clinical presentation consistent with TCR during BSSO. Awareness of this potential association, prompt recognition, effective communication between the surgical and anaesthesiology teams, and timely management are essential for favourable outcomes.
No takes yet. Share an insight, caveat, or question.
Pise et al. (2026) conducted a case report in Asystole / Trigeminocardiac reflex (n=1). Bilateral sagittal split osteotomy (BSSO) was evaluated on Asystole. Bilateral sagittal split osteotomy triggered a trigeminocardiac reflex resulting in intraoperative asystole in a teenage girl, which was successfully reversed with prompt cardiopulmonary resuscitation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: