Key result
Noninvasive myocardial work analysis assumes peak left ventricular systolic pressure approximates brachial systolic blood pressure, an assumption that may not hold in left ventricular outflow tract obstruction.
Why the study?
Should the Doppler gradient be added to noninvasive myocardial work assessment in pediatric patients with subaortic stenosis?
Should the Doppler gradient be added to noninvasive myocardial work assessment in pediatric patients with subaortic stenosis?
The assumption that peak left ventricular systolic pressure approximates brachial systolic blood pressure in myocardial work analysis may be invalid in pediatric subaortic stenosis due to the presence of a pressure gradient.
Noninvasive myocardial work (MW) analysis using pressure-strain loops has emerged as a novel echocardiographic tool for assessing left ventricular (LV) function.1-3 The method assumes that peak LV systolic pressure approximates brachial systolic blood pressure (BP)4; however, this assumption may not hold in the presence of left ventricular outflow tract (LVOT) obstruction, in which a pressure gradient exists between the LV and the systemic circulation.5
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Sammaan et al. (2026) studied Pediatric Subaortic Stenosis. Noninvasive myocardial work (MW) analysis was evaluated. Noninvasive myocardial work analysis assumes peak left ventricular systolic pressure approximates brachial systolic blood pressure, an assumption that may not hold in left ventricular outflow tract obstruction.
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