Circulating fatty acids in STEMI and hypertension: disease signatures or metabolic confounding?

Q: What does this research mean for the field?

Distinct circulating free fatty acid profiles observed in STEMI and hypertension may reflect underlying metabolic confounding rather than genuine disease-specific signatures. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Güney Sarıoğlu

doi:10.1080/00015385.2026.2735577

September 19, 2026Acta cardiologica. Supplementum

Circulating fatty acids in STEMI and hypertension: disease signatures or metabolic confounding?

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Key result

Circulating free fatty acid profiles are distinct among patients with ST-segment elevation myocardial infarction, systemic arterial hypertension, and healthy controls.

Key Points

Determine whether circulating free fatty acid profiles represent distinct disease signatures or reflect metabolic confounding in myocardial infarction and hypertension.
Analyzed circulating free fatty acid profiles across patients with ST-segment elevation myocardial infarction, systemic arterial hypertension, and healthy controls.
Identified distinct circulating free fatty acid profiles that distinguish patients with ST-segment elevation myocardial infarction and hypertension from healthy controls.
Showed that specific fatty acid alterations raise questions regarding whether they act as true pathological biomarkers or metabolic confounders.

Structured PICO

P

Population

Patients with ST-segment elevation myocardial infarction (STEMI), systemic arterial hypertension (SAH), and healthy controls

O

Outcome

Circulating free fatty acid (FFA) profilessurrogate

Implication

Highlights distinct circulating free fatty acid profiles in patients with STEMI and hypertension, raising questions about their role as disease signatures versus metabolic confounders.

Abstract

Baldi et al. report distinct circulating free fatty acid (FFA) profiles in patients with ST-segment elevation myocardial infarction (STEMI), systemic arterial hypertension (SAH), and healthy contro...

Discussion

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Cite This Study

Güney Sarıoğlu (2026) studied this question. Circulating free fatty acid profiles are distinct among patients with ST-segment elevation myocardial infarction, systemic arterial hypertension, and healthy controls.

synapsesocial.com/papers/6ad0fd1915427f6a8404048c https://doi.org/10.1080/00015385.2026.2735577

View at Publisher

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Circulating fatty acids in STEMI and hypertension: disease signatures or metabolic confounding?

Key Points

Structured PICO

Implication

Abstract

Discussion

Cite This Study

Circulating fatty acids in STEMI and hypertension: disease signatures or metabolic confounding?

Key Points

Structured PICO

Implication

Abstract

Discussion

Cite This Study

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