Key result
Multimarker lipid profiling best captures residual cardiovascular risk in metabolic syndrome.
Why the study?
Atherosclerotic cardiovascular disease combined with metabolic syndrome presents a complex lipoprotein phenotype inadequately reflected by LDL-C alone, necessitating evaluation of traditional and calculated lipid indices for residual cardiovascular risk assessment.
Review reveals calculated lipid indices assess residual cardiovascular risk in metabolic syndrome, highlighting limitations of low-density lipoprotein cholesterol alone.
превентивной медицины № 1» Ташкентского государственного медицинского университета.
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Makhkamova et al. (2026) conducted a review in Cardiovascular disease and metabolic syndrome. Lipid and atherogenic indices (non-HDL-C, ApoB, TG/HDL-C, AIP, remnant cholesterol, TyG) vs. Standard LDL-C assessment was evaluated. A multimarker approach utilizing LDL-C, non-HDL-C, ApoB, and triglyceride-dependent indices optimally characterizes residual risk in patients with cardiovascular disease and metabolic syndrome.
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