Key result
Dilated cardiomyopathy clinical severity (NYHA class) was significantly associated with left ventricular end-diastolic diameter (p=0.001) and ejection fraction (p=0.001).
Why the study?
Dilated cardiomyopathy presents with varying clinical, electrocardiographic, and echocardiographic features, requiring comprehensive assessment to understand severity and cardiac abnormalities.
Cross-Sectional (n=100)
No
Clinical severity as assessed by NYHA class in patients with dilated cardiomyopathy is significantly associated with left ventricular end-diastolic dimension and ejection fraction.
Answers are grounded in this paper and cite their sources.
DCM clinical-ECG-echocardiographic correlations are hypothesis-generating; leaves open causal links and prognostic utility pending longitudinal data.
Background: Dilated cardiomyopathy (DCM) is characterized by ventricular dilatation and impaired systolic function and may present with varying degrees of heart failure, arrhythmia, and structural cardiac abnormalities. Clinical examination, electrocardiography (ECG), and echocardiography are important for comprehensive assessment. Aim: To evaluate the clinical presentation, ECG abnormalities, and echocardiographic changes in patients with DCM and to assess the relationship between clinical severity and cardiac imaging findings. Materials and Methods: A prospective cross-sectional study was conducted in the Department of General Medicine, Katihar Medical College and Hospital, Bihar, from September 2024 to February 2026. A total of 100 patients aged >18 years with confirmed DCM were included. Clinical examination, 12-lead ECG, and transthoracic echocardiography were performed. Results: The mean age was 49.65 ± 18.50 years, with 65% males and 35% females. NYHA Class II was most common (50%). Breathlessness (87%), fatigue (75%), and pedal edema (72%) were the leading symptoms. Rhythm abnormalities and conduction defects occurred in 76% each. LVEDD was ≥60 mm in 31%, while EF was 20–29% in 39%. Significant associations were observed between NYHA class and LVEDD (p=0.001) and EF (p=0.001), whereas LVESD was not significant (p=0.055). Conclusion: Clinical assessment combined with ECG and echocardiography effectively characterizes DCM severity and identifies important structural and functional abnormalities.
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Sharma et al. (2026) conducted a cross-sectional in Dilated cardiomyopathy (DCM) (n=100). Clinical and echocardiographic characteristics of DCM was evaluated on Relationship between NYHA class and echocardiographic parameters (LVEDD and EF) (p=0.001). Dilated cardiomyopathy clinical severity (NYHA class) was significantly associated with left ventricular end-diastolic diameter (p=0.001) and ejection fraction (p=0.001).
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