Key result
Case report highlights overlapping clinical and imaging features of concurrent SCAD and stress-induced cardiomyopathy.
Why the study?
The relationship between spontaneous coronary artery dissection and stress-induced cardiomyopathy remains poorly understood despite their increasing recognized coexistence.
Case Report (n=1)
SCAD and stress-induced cardiomyopathy can concurrently present in women with acute coronary syndrome, highlighting the need to evaluate for wall motion abnormalities extending beyond a single coronary territory.
Answers are grounded in this paper and cite their sources.
Concurrent SCAD and stress-induced cardiomyopathy may overlap in perimenopausal ACS; hypothesis-generating and leaves open need for prospective studies before practice change.
Spontaneous coronary artery dissection (SCAD) and stress-induced cardiomyopathy (SICM) are nonatherosclerotic causes of acute coronary syndrome that predominantly affect women.Their overlapping clinical, electrocardiographic, biomarker, and imaging features can make diagnosis challenging, and although their coexistence is increasingly recognized, the relationship between these entities remains poorly understood.A 48-year-old female with cardiovascular risk factors presented with back and scapular pain and ST-segment elevations.Coronary angiography revealed Yip-Saw Class 2 SCAD in the mid-distal LAD with preserved flow.Echocardiography demonstrated wall motion abnormalities extending beyond the LAD territory with a reduced ejection fraction and apical ballooning suggesting concurrent SICM.This case illustrates the concept that SCAD and SICM are important non-atherosclerotic causes of acute coronary syndrome in women and may present with overlapping features that complicate diagnosis.Their coexistence is biologically plausible given their marked female predominance and shared susceptibility related to estrogen-mediated vascular protection, which may be diminished during the perimenopausal transition.Clinicians should consider concurrent SICM when evaluating patients with SCAD, particularly when wall motion abnormalities extend beyond the affected coronary distribution.
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Panyala et al. (2026) conducted a case report in Spontaneous coronary artery dissection (SCAD) and stress-induced cardiomyopathy (SICM) (n=1). Concurrent spontaneous coronary artery dissection and stress-induced cardiomyopathy was evaluated. A 48-year-old perimenopausal woman presented with concurrent spontaneous coronary artery dissection and stress-induced cardiomyopathy, highlighting their overlapping clinical and imaging features.
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