Key result
A Risk of Reporting metric comparing common anaesthetic agents to propofol has been established to inform future research on their association with perioperative cardiac arrest.
Why the study?
Do specific common anaesthetic agents alter the risk of perioperative cardiac arrest compared to propofol?
Do specific common anaesthetic agents alter the risk of perioperative cardiac arrest compared to propofol?
Discusses a novel Risk of Reporting metric that can inform future research into the safety of specific anesthesia medications and their risk for perioperative cardiac arrest.
The WHO VigiBase is a worldwide registry of cardiac arrests associated with anaesthesia cases. Using data from VigiBase, Perez and Fettiplace established a Risk of Reporting (RoR) metric for each common anaesthetic agent, comparing the occurrence of cardiac arrest associated with a given agent relative to its reported use in the database with propofol as the reference agent. This 'RoR' metric can inform future research into the association between specific anaesthesia medications and the risk for perioperative cardiac arrest.
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O’Connor et al. (2026) conducted an editorial in Perioperative cardiac arrest. Anaesthetic agents vs. Propofol was evaluated on Cardiac arrest. A Risk of Reporting metric comparing common anaesthetic agents to propofol has been established to inform future research on their association with perioperative cardiac arrest.
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