Key result
Post-TAVR hypoattenuated leaflet thickening represents a common imaging finding that may progress to valve dysfunction.
Why the study?
The expansion of TAVR into younger and lower-risk populations has increased focus on long-term valve durability and the clinical implications of hypoattenuated leaflet thickening.
Hypoattenuated leaflet thickening (HALT) is increasingly recognized as a post-TAVR imaging finding on CT that represents a spectrum of subclinical leaflet thrombosis with potential for progression to valve dysfunction.
The expansion of transcatheter aortic valve replacement (TAVR) into younger and lower-risk populations has heightened attention toward long-term valve durability. Hypoattenuated leaflet thickening (HALT), a subclinical imaging finding identified on multidetector computed tomography, has emerged as a relatively common occurrence following TAVR. It is characterized by low-attenuation, often meniscal-shaped thickening of bioprosthetic valve leaflets and may be present with or without associated reduced leaflet motion. Although frequently asymptomatic, HALT is increasingly recognized as part of a broader spectrum of leaflet thrombosis that may progress to clinically significant valve dysfunction.
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Madanat et al. (2026) conducted a review in Hypoattenuated leaflet thickening following transcatheter aortic valve replacement. Hypoattenuated leaflet thickening is a relatively common subclinical imaging finding following TAVR that is increasingly recognized as potentially progressing to clinically significant valve dysfunction.
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