Key result
Primary cardiac fibroma causes fatal arrhythmia in infant via left bundle branch compression.
Why the study?
Cardiac fibroma in infants can cause fatal arrhythmia and death despite being histopathologically benign, highlighting the need for awareness of this cause of sudden infant death.
Case Report (n=1)
Primary cardiac fibroma, although histopathologically benign, can compress the conduction system and cause fatal arrhythmia and sudden death in infants.
Prompts consideration of cardiac fibroma in unexplained infant arrest; case report leaves open systematic screening needs.
• Cardiac fibroma in infants can cause fatal arrhythmia and death. • Cardiac fibroma is a benign tumor in terms of histopathology. • Among primary cardiac tumors, cardiac fibroma is the second most commonly occurring. A one-month-old girl in good health being carried by her mother in a baby carrier suddenly went into cardiac arrest. She was rushed to the hospital, but was pronounced dead. A forensic autopsy was performed. On the heart, which weighed 63.6 g, a single large, well-defined, round, white tumor was observed in the left ventricular wall. Tumor cells with spindle-shaped small nuclei proliferated along with collagen fiber proliferation. The diagnosis was cardiac fibroma. The tumor had compressed the left bundle branch, causing fatal arrhythmia and death. This case report describes sudden infant death caused by a primary cardiac fibroma, diagnosed postmortem.
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Irie et al. (2025) conducted a case report in Cardiac fibroma (n=1). Cardiac fibroma was evaluated on Sudden infant death and fatal arrhythmia. A postmortem autopsy of a one-month-old girl with sudden infant death revealed a primary cardiac fibroma compressing the left bundle branch and causing fatal arrhythmia.
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