Key result
Severe mitral regurgitation and LVOT obstruction resolve spontaneously after NSTEMI in new HCM.
Why the study?
The clinical dilemma of managing hypertrophic cardiomyopathy with intermittent free mitral regurgitation and LVOT obstruction due to transient ischemic etiology is not well described.
Case Report (n=1)
Answers are grounded in this paper and cite their sources.
We describe the case of a 52-year-old woman presenting with non-ST elevation myocardial infarction, atrial fibrillation, and a new diagnosis of hypertrophic cardiomyopathy. Transesophageal echocardiography following hemodynamic deterioration revealed completely restricted mitral leaflet motion with free mitral regurgitation, and severe left ventricular outflow tract (LVOT) obstruction. Surgical intervention was considered; however, repeat imaging following a period of clinical stability revealed resolution of the findings suggesting a transient ischemic etiology. The case is supported by clinical and echocardiographic images with movie clips, and a discussion of the likely pathology in the context of the underlying condition.
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Gibson et al. (2014) conducted a case report in Hypertrophic cardiomyopathy with non-ST elevation myocardial infarction and atrial fibrillation (n=1). A 52-year-old woman with new hypertrophic cardiomyopathy and NSTEMI developed transient severe mitral regurgitation and LVOT obstruction that resolved spontaneously.
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