Key result
Refractory hypertension represents a distinct, rare phenotype of treatment failure on maximal antihypertensive therapy.
Why the study?
The terms refractory and resistant hypertension were long considered interchangeable, but refractory hypertension is now recognized as a distinct phenotype of antihypertensive treatment failure with unique characteristics and etiologies.
Answers are grounded in this paper and cite their sources.
Refractory hypertension may warrant distinct evaluation; leaves open optimal therapies and prognosis pending prospective data.
Refractory hypertension is a novel phenotype of antihypertensive treatment failure. The terms "refractory hypertension" and "resistant hypertension" were considered interchangeable for a long time and related to difficult-to-treat hypertension. Recently, the term "refractory hypertension" refers to a very small group of patients who do not really reach the target blood pressure for maximum antihypertensive therapy. In this review we discuss similarities and contrasts definition, prevalence, patient characteristics, risk factors, and possible underlying etiologies of refractory and resistant hypertension.
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Владимировна et al. (2018) conducted a review in Refractory and resistant hypertension. Refractory hypertension vs. Resistant hypertension was evaluated. Refractory hypertension is a distinct phenotype of antihypertensive treatment failure affecting a very small group of patients who do not reach target blood pressure on maximum therapy.
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