Key result
Preoperative mechanical ventilation in TOF-APVS is linked to higher early postoperative mortality.
Why the study?
Congenital absence of the pulmonary valve presents a characteristic clinical, physiologic, and pathologic syndrome in tetralogy of Fallot that requires further description.
Observational (n=27)
No
Absolute Event Rate: 40% vs 31.8%
p-value: p=1.000
May signal need for intensified perioperative care in ventilated TOF-APVS cases; hypothesis-generating for preoperative risk stratification in this rare population.
A group of cases of tetralogy of Fallot with congenital absence of the pulmonary valve are presented, and it is indicated that this abnormality presents a characteristic clinical, physiologic, and pathologic syndrome. It is postulated that the aneurysmal dilatation of the pulmonary artery may result either from a congenital weakness at the base of the pulmonary artery or from the hemodynamic effects of a ventricular septal defect and infundibular stenosis in the presence of pulmonary regurgitation. The absence of the pulmonary valve has not been a deterrent to successful corrective surgery aimed at the basic pathology of tetralogy of Fallot in three cases.
No takes yet. Share an insight, caveat, or question.
Miller et al. (1962) conducted an observational in Tetralogy of Fallot with absent pulmonary valve syndrome (TOF-APVS) (n=27). Preoperative mechanical ventilation vs. No preoperative mechanical ventilation was evaluated on Need for any reintervention during follow-up (p=1.000).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: