Cohort (n=656)
Yes
Longitudinal increases in blood pressure, rather than initial baseline levels, independently drive the progression of arterial stiffness in healthy middle-aged men.
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Cohn et al. (2004) conducted a cohort in Healthy (no cardiovascular or severe diseases) (n=656). Longitudinal increase in systolic blood pressure vs. Unexposed/reference (no longitudinal increase) was evaluated on Relative annual change in brachial-ankle pulse wave velocity (baPWV) > 1% (OR 1.34, 95% CI 1.22-1.46, p=<.001).
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