I read with great interest Clarkson and Choonara’s paper on the fatal suspected adverse drug reactions (ADRs) in the UK, and I strongly agree with their conclusions, namely that an evidence based approach to drug treatment is needed to minimise fatalities due to drug toxicity in children.1 However, recent evidence also suggests that we are now ready for a gene based approach to drug treatment allowing to further minimise the occurrence and the severity …
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Mario Impicciatore (2003) studied this question.
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