Why the study?
Does assessing the pullback pressure gradient (PPG) help predict future adverse events like plaque rupture in ischemia-negative coronary lesions?
Does assessing the pullback pressure gradient (PPG) help predict future adverse events like plaque rupture in ischemia-negative coronary lesions?
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“PPG may identify high-risk patterns even in lesions that are ischemia negative by traditional thresholds, raising the possibility that disease patterns, independently from absolute FFR values, may carry prognostic implications.”
A high pullback pressure gradient (PPG) may reflect focal mechanical stress and predict future plaque rupture and acute coronary syndromes even in the absence of ischemia.
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Ando et al. (2025) studied this question.
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