Key result
Post-TAVI leaflet thrombosis occurs in ~1% of patients and generally resolves with DOAC therapy.
Why the study?
There are limited reports on the occurrence of sub-acute clinical leaflet thrombosis (HALT) following TAVI while on direct oral anticoagulants and its treatment.
Answers are grounded in this paper and cite their sources.
Highlights the rare occurrence of sub-acute clinical leaflet thrombosis (HALT) following TAVI despite active treatment with DOACs.
The incidence of leaflet thrombosis following transcatheter aortic valve implantation is about 1% and is generally effectively treated with direct oral anticoagulants (DOACs). However, there are limited reports on the occurrence of HALT whilst on DOACs and its treatment.
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Nishimura et al. (2026) studied this question. Leaflet thrombosis after transcatheter aortic valve implantation occurs in about 1% of patients and is generally effectively treated with direct oral anticoagulants.
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