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•A chromosome-scale genome assembly of Nmpelopsis grossedentata provides a foundational genomic resource.•Karyotype analysis positions N. grossedentata as having a karyotype most closely resembling the Ancestral Eudicot Karyotype (AEK) than Muscadinia rotundifolia or V itis vinifera.•This study offers key insights into the genomic basis of flavonoid biosynthesis and karyotype evolution in plants.
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Li et al. (2026) studied this question.
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