Key result
Psoriasis is linked to higher carotid QIMT than psoriatic arthritis, correlating with CV risk.
Why the study?
Ultrasound detects joint ecostructural damage and vascular alterations in psoriasis and psoriatic arthritis, motivating an evaluation of the correlation between inflammatory nail ultrasound findings, radiofrequency-assessed carotid intima-media thickness, and clinical and laboratory findings.
Cross-Sectional (n=30)
No
Hypothesis-generating for differential carotid atherosclerosis in psoriasis versus psoriatic arthritis; leaves open incremental value of QIMT over Framingham score.
BACKGROUND: Ultrasound (US) in psoriasis (PsO) and psoriatic arthritis (PsA) is an important tool in several situations to detect joint ecostructural damage as well as other tissue alterations, such as those that occur in the larger vessels. The objective of this study was to detect and correlate the changes that indicate the inflammatory and atherosclerotic process in two groups of patients, using nail US and carotid artery intima-media thickness radiofrequency (RF) software. CONCLUSION: The use of US in the evaluation of these patients showed significant correlations between clinical and laboratory measures, characterized by QIMT and FS as well as changes in nail insertion. Future studies may demonstrate an even better interaction.
No takes yet. Share an insight, caveat, or question.
Mendonça et al. (2020) conducted a cross-sectional in Psoriasis and psoriatic arthritis (n=30). Psoriasis (PsO) evaluated via nail ultrasound and carotid RF-QIMT vs. Psoriatic arthritis (PsA) was evaluated on Carotid artery quality intima-media thickness (QIMT expected) and correlation with Framingham Score and LDL (r=0.677 (QIMT expected with Framingham Score); r=0.633 (QIMT-RF with LDL), p=0.006). Carotid ultrasound QIMT was higher in psoriasis than psoriatic arthritis (56.25% vs 40%, p=0.006) and correlated with Framingham Score (r=0.677, BF=10.06) and LDL (r=0.633, BF=3.70).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: