Key result
Psoriasis was associated with significantly higher averaged common carotid artery intima-media thickness compared with healthy controls (0.609 vs. 0.526 mm; P=0.003).
Why the study?
Is psoriasis associated with increased subclinical atherosclerosis and impaired endothelial function compared to healthy controls?
Population
86 subjects. Excluded: diabetes mellitus, hypertension, renal failure, history of cardiovascular or…
Comparison
Presence of psoriasis vulgaris vs Healthy controls matched for age and sex
Design
Case-control
Authors
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Psoriasis-linked cIMT increase may signal elevated CV risk; leaves open whether targeted screening improves outcomes.
Case-Control (n=86)
Is psoriasis associated with increased subclinical atherosclerosis and impaired endothelial function compared to healthy controls?
Absolute Event Rate: 0.609% vs 0.526%
p-value: p=0.003
Psoriasis is an independent risk factor for subclinical atherosclerosis, characterized by increased carotid intima-media thickness and impaired endothelial function.
Balci et al. (2008) conducted a case-control in Psoriasis (n=86). Psoriasis vs. Healthy controls was evaluated on Averaged common carotid artery intima-media thickness (IMT) (p=0.003). Psoriasis was associated with significantly higher averaged common carotid artery intima-media thickness compared with healthy controls (0.609 vs. 0.526 mm; P=0.003).
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