Key result
Mondays are linked to ~1 additional coronary event per 100 weekly events, likely reflecting coding artifacts.
Why the study?
The size and possible causes of the reported excess in coronary events on Mondays required investigation.
Meta-Analysis
Yes
Answers are grounded in this paper and cite their sources.
Small Monday excess likely artifactual; challenges prior weekday variation reports and underscores registry data validation needs.
BACKGROUND: The aim of this article was to investigate the size and possible causes of the reported excess in coronary events on Mondays. METHODS: We conducted a metaanalysis of data from the World Health Organization (WHO) MONICA Project, which monitored trends and determinants in cardiovascular disease. The MONICA Project was undertaken in 21 countries from 1980 to 1995. RESULTS: We found a small overall excess rate of coronary events on Mondays. In a population experiencing 100 events per week, we estimate there would be approximately 1 more event on Monday than on any other day. Hierarchical logistic regression showed that the Monday excess was greater in centers with less thorough data collection procedures. CONCLUSIONS: The excess of coronary events on Mondays is probably an artifact resulting from events with uncertain dates being coded as taking place on Mondays.
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Barnett et al. (2004) conducted a meta-analysis in Coronary events. Monday (day of the week) vs. Other days of the week was evaluated on Excess rate of coronary events on Mondays (Approximately 1 additional event on Monday per 100 weekly events). Mondays were associated with a small excess of ~1 additional coronary event per 100 weekly events compared to other days, likely due to coding artifacts in centers with less thorough data collection.
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