Key result
Emboliner protection achieves >90% vegetation removal without embolic events during AngioVac debulking for endocarditis.
Why the study?
Percutaneous debulking of left-sided endocarditis and thrombus has previously relied on cerebral-only embolic protection devices, and the use of the Emboliner whole-body embolic protection filter during aortic and combined tricuspid/mitral endocarditis debulking had not been reported.
Case Report (n=2)
This case report demonstrates the first successful use of whole-body embolic protection with the Emboliner filter as an adjunct to AngioVac-based percutaneous debulking of aortic and combined tricuspid/mitral valve endocarditis, achieving >90% vegetation removal without embolic complications.
Feasibility of whole-body embolic protection in endocarditis debulking shown in 2 cases; leaves open clinical benefit in larger trials.
BACKGROUND: Percutaneous debulking of left-sided endocarditis and thrombus has previously relied on cerebral-only embolic protection devices. The Emboliner is an investigational nitinol-mesh filter that provides whole-body embolic protection and has been studied in transcatheter aortic valve replacement. SUMMARY: We describe its first reported use as an adjunct to AngioVac-based debulking in 2 patients: 1 with aortic valve endocarditis and 1 with combined tricuspid and mitral endocarditis. DISCUSSION: The Emboliner was successfully deployed in both cases, with over 90% of vegetation removed and no periprocedural or in-hospital embolic events. Deployment technique differed by vegetation location: in the aortic valve case, the AngioVac cannula was advanced through the filter's access port; in the tricuspid/mitral case, no further interaction with the filter was required once deployed. NOVELTY: This represents, to our knowledge, the first reported use of whole-body embolic protection during aortic and combined tricuspid/mitral percutaneous endocarditis debulking. TAKE-HOME MESSAGE: Whole-body embolic protection may offer an important adjunct to percutaneous debulking in patients at high surgical risk.
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Younes et al. (2026) conducted a case report in Valvular endocarditis (aortic valve endocarditis in 1 patient, combined tricuspid and mitral endocarditis in 1 patient) (n=2). Emboliner whole-body embolic protection device as an adjunct to AngioVac-based debulking was evaluated on Procedural success, vegetation removal, and periprocedural or in-hospital embolic events. Emboliner whole-body embolic protection during AngioVac debulking in 2 endocarditis patients achieved >90% vegetation removal with 0% periprocedural or in-hospital embolic events.
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