Key result
Complex Korean medicine eliminates AF burden in an antiarrhythmic-refractory patient in a case report.
Why the study?
This case report aimed to describe the management of asymptomatic, antiarrhythmic-refractory AF using a complex Korean medicine treatment regimen evaluated with 72-hour patch-type Holter monitoring.
Does a 7-week complex Korean medicine regimen including Sayeok-san reduce atrial fibrillation and supraventricular ectopic burden on 72-hour Holter monitoring in an older adult with antiarrhythmic-refractory asymptomatic atrial fibrillation?
Case Report (n=1)
No
Does a 7-week complex Korean medicine regimen including Sayeok-san reduce atrial fibrillation and supraventricular ectopic burden on 72-hour Holter monitoring in an older adult with antiarrhythmic-refractory asymptomatic atrial fibrillation?
In a single patient with antiarrhythmic-refractory asymptomatic atrial fibrillation, a 7-week adjunctive Korean medicine regimen including modified Sayeok-san and acupuncture was associated with complete resolution of AF episodes (from 8.61% to 0%) and a marked reduction in supraventricular ectopic burden (from 6.19% to 0.57%) on 72-hour Holter monitoring.
Complete AF suppression in one refractory case; leaves open efficacy of Korean medicine adjuncts pending prospective trials.
Objectives: To report a case of asymptomatic atrial fibrillation (AF) in which AF suppression and reduced supraventricular ectopic (SVE) burden were achieved with complex Korean medicine (KM) treatment.Case presentation: A male patient in his late 70s with antiarrhythmic-refractory AF received a 7-week KM regimen consisting of acupuncture and sequential herbal treatment with modified Sihogyejigeongang-tang followed by Sayeok-san-based formulas. Treatment response was evaluated using pretreatment and posttreatment 72-hour Holter monitoring. Baseline monitoring showed an AF burden of 8.61% and an SVE burden of 6.19% (18,129 beats). On Day 49, follow-up monitoring demonstrated no detectable AF episodes (AF burden, 0%) and a reduced SVE burden of 0.57% (1,704 beats).Conclusions: Complex KM centered on modified Sayeok-san may represent a viable alternative for managing asymptomatic AF and reducing arrhythmic triggers, although further controlled studies are warranted.
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Choi et al. (2026) conducted a case report in Asymptomatic antiarrhythmic-refractory atrial fibrillation and supraventricular ectopic beats (n=1). Complex Korean medicine treatment (acupuncture, electroacupuncture, cupping, moxibustion, infrared therapy, and sequential herbal medicine including modified Sihogyejigeongang-tang and Sayeok-san-based formulas) was evaluated on Atrial fibrillation (AF) burden on 72-hour patch-type Holter monitoring at Day 49. Complex Korean medicine treatment reduced atrial fibrillation burden from 8.61% to 0% and supraventricular ectopic burden from 6.19% to 0.57% after 7 weeks in an antiarrhythmic-refractory patient.
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