Why the study?
A single bout of aerobic exercise transiently improves vascular function whereas binge drinking impairs endothelial function, leaving it unclear whether alcohol consumption during post-exercise recovery attenuates the acute vascular benefits of exercise.
Does post-exercise binge drinking attenuate exercise-induced improvements in brachial artery flow-mediated dilation in healthy young men?
Does post-exercise binge drinking attenuate exercise-induced improvements in brachial artery flow-mediated dilation in healthy young men?
Post-exercise binge drinking reverses the acute improvements in endothelial function normally seen after a single bout of moderate-intensity aerobic exercise in healthy young men.
This is the authors' abstract. We don't add key points for this paper.
Background A single bout of aerobic exercise (AE) transiently improves vascular function, whereas binge drinking impairs endothelial function. However, whether alcohol consumption during post-exercise recovery attenuates the acute vascular benefits of exercise remains unclear. We hypothesized that post-exercise binge drinking would blunt exercise-induced improvements in vascular function. Methods In this randomized cross-over trial, 14 healthy young men (25.1 ± 2.4 years) completed 2 experimental conditions in randomized order. Participants performed 30 minutes of moderate-intensity treadmill exercise (55–60% heart rate reserve), followed by consumption of either 360 mL of water or Korean soju (~60 g of ethanol) with 10 g of dried pollack over 30 minutes. The primary outcome was brachial artery flow-mediated dilation (FMD), and carotid-femoral pulse wave velocity (cfPWV) was assessed as a measure of arterial stiffness. Outcomes were measured at baseline and 1 and 2 hours after exercise. Results All 14 participants completed both conditions and were included in the analyses. FMD increased following exercise in the water condition (6.1 ± 1.8% at baseline to 8.8 ± 2.3% at 2 hours) but decreased following alcohol consumption (6.6 ± 2.6% at baseline to 4.0 ± 2.9% at 2 hours), with a significant condition × time interaction (*P* < 0.001). In contrast, cfPWV showed a significant time effect (*P* = 0.008), with no significant condition × time interaction. Conclusions Post-exercise binge drinking attenuated improvements in endothelial function following a single bout of AE, whereas no differential cfPWV response was observed between conditions. These findings suggest that binge drinking during recovery may diminish the immediate vascular benefits of exercise.
Post-exercise binge drinking reverses acute FMD gains; challenges post-exercise alcohol safety and extends vascular effect data in young men.
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Han et al. (2026) studied this question.
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