Key result
Intraoperative TEE misses acute main pulmonary embolism despite severe refractory hypoxia during surgery.
Why the study?
Intraoperative pulmonary embolism is a rare, potentially fatal complication, and although transesophageal echocardiography is a principal intraoperative imaging tool for evaluating suspected PE, its sensitivity depends on thrombus location and patient factors.
Case Report (n=1)
No
This case report highlights the limitations of intraoperative transesophageal echocardiography for detecting pulmonary embolism and warns against false reassurance from a technically limited study when indirect signs such as right ventricular dilation and a widened PaCO2-EtCO2 gradient are present.
Nondiagnostic intraoperative TEE does not exclude acute PE; leaves open questions on optimal perioperative imaging in high-risk orthopedic patients.
Intraoperative pulmonary embolism (PE) is a rare but potentially fatal perioperative complication, particularly in lower extremity orthopedic surgery. Transesophageal echocardiography (TEE) is a principal intraoperative bedside imaging tool for evaluating suspected PE; however, its sensitivity depends on thrombus location and patient factors. We present a 32-year-old man with morbid obesity who developed hypoxia refractory to 100% fraction of inspired oxygen (FiO₂), recruitment maneuvers and increased positive end-expiratory pressure (PEEP), with presumed hypotension, during open reduction and internal fixation of a left ankle fracture. Intraoperative TEE was nondiagnostic and reported normal biventricular size and function, whereas an earlier transthoracic study had shown right ventricular dilation. Postoperative CT angiography showed an acute PE in the right main pulmonary artery extending into bilateral segmental and subsegmental arteries, with right heart strain. The patient underwent successful mechanical thrombectomy and was discharged on anticoagulation. This case highlights the limits of TEE for detecting intraoperative PE, the hazard of false reassurance from a technically limited study, and the value of indirect signs such as a widened arterial–end-tidal carbon dioxide (PaCO₂–EtCO₂) gradient and right ventricular dilation.
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Nair et al. (2026) conducted a case report in Intraoperative pulmonary embolism (n=1). Intraoperative transesophageal echocardiography (TEE) vs. Postoperative CT angiography was evaluated on Detection of acute pulmonary embolism. Intraoperative transesophageal echocardiography was nondiagnostic in a 32-year-old man with refractory hypoxia on 100% FiO2, preceding CT-confirmed acute right main pulmonary embolism.
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