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Intraductal oncocytic papillary neoplasm (IOPN) is a rare intraductal pancreatic tumor that is difficult to diagnose preoperatively using imaging, and a definitive diagnosis depends on pathology and immunophenotype. Complete resection remains the primary treatment. For cases of carefully evaluated localized IOPN, a function-preserving surgery like laparoscopic duodenum-preserving pancreatic head resection might be a safe and feasible option in highly experienced clinical centers. In this study, we retrospectively analyzed the symptoms, imaging features, surgical procedures, pathological and immunohistochemical results of a patient with IOPN in the pancreatic head and reviewed the relevant literature.
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Liu et al. (2026) studied this question.
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