3, 4, 9, 10-perylene tetracarboxylic acid functionalized MoS2 nanocomposite as peroxidase mimic for the detection of H2O2 and glucose

This is the authors' abstract. We don't add key points for this paper.

The 3, 4, 9, 10-perylene tetracarboxylic acid (PTCA) functionalized MoS2 nanocomposite (PTCA-MoS2) was synthesized via the hydrothermal method, and its structural and catalytic properties were investigated. The results demonstrated that PTCA-MoS2 exhibits enhanced peroxidase-mimicking activity and efficiently catalyzes the reaction of H2O2 oxidizing 3, 3′, 5, 5′- tetramethyl benzidine (TMB). Notably, owing to the synergistic interaction between PTCA and MoS2, the incorporation of PTCA significantly enhances the peroxidase-mimicking activity of MoS2. The experimental conditions were optimized, and the peroxidase-mimicking activity of PTCA-MoS2 followed Michaelis-Menten kinetics. Additionally, fluorescent probe experiments confirmed that hydroxyl radicals (·OH) play a crucial role in the catalytic reaction process. Based on these findings, a facile colorimetric sensing platform was established for the detection of glucose and H2O2, achieving low limits of detection (LODs) of 0.61 μM and 0.47 μM, respectively.