Background: Osteoporosis is a systemic skeletal disease characterized by reduced bone mineral density and alterations in bone microarchitecture. Purpose: To assess estimated osteoporosis risk using mandibular cortical width (MCW) obtained from cone-beam computed tomography (CBCT) scans in subjects older than 40 years and to analyze its association with age and sex. Methods: A retrospective cross-sectional observational study was conducted using a source population of 3,852 CBCT scans; 349 scans that met the eligibility criteria were consecutively selected and comprised the sample. MCW was measured with iRYS Viewer version 11.5. Intra-observer reproducibility was estimated using the intraclass correlation coefficient. Data were analyzed in IBM SPSS Statistics 27.0 using descriptive statistics, Pearson chi-square test, Spearman correlation, and binary logistic regression. Results: Eight percent of subjects showed estimated osteoporosis risk according to MCW. Subjects aged ≥ 66 years had higher odds of estimated risk than those aged 40-65 years (OR = 2.50; 95% CI: 1.02-6.11; p = 0.04). Female sex was associated with higher odds of estimated risk than male sex (OR = 3.23; 95% CI: 1.33-7.86; p = 0.009). Conclusions: MCW measured on CBCT identified 8% of subjects with estimated osteoporosis risk, with a higher frequency among women and individuals aged ≥ 66 years.
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Bermeo-Aguilar et al. (2026) studied this question.
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