Key result
Abdominal obesity is linked to ~2.1-fold higher 10-year cardiovascular risk alongside hypertension and hypertriglyceridemia.
Why the study?
The association between metabolic syndrome-related indicators and the 10-year risk for cardiovascular disease in middle-aged and elderly populations needed exploration.
Cross-Sectional
Metabolic syndrome indicators were associated with higher 10-year CVD risk; leaves open their added value for prediction or intervention in Asian elderly.
Objectives. This study explored the association between metabolic syndrome-related indicators and the ten-year risk for cardiovascular disease (CVD) in the middle-aged and elderly population. Methods. Data were collected from residents in Southern Taiwan through a health screening program, carried out from March 2007 to May 2008. The present study used the risk assessment tool of the Framingham Heart Study and adopted ≦10% as low risk, 11~20% as medium risk, and > 20% as high risk for CVD. Results. We found that subjects with abdominal obesity and hypertension had significantly higher 10-year risk for CVD than those who had normal waist circumference and blood pressure ( OR=2.07 and 24.52, resp.). Subjects with hypertriglyceridemia were 1.86 times more at risk for developing medium risk of CVD than those who had normal triglyceride levels. Furthermore, individuals with reduced high-density lipoprotein cholesterol (HDL-C) had significantly higher 10-year risk for CVD than those who had normal HDL-C. Conclusions. Metabolic syndrome-related indicators were positively associated with 10-year risk for CVD. Waist circumference (WC), blood pressure, triglyceride and HDL-C might be good indicators for predicting the risk of CVD for middle-aged and elderly populations.
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Yang et al. (2011) conducted a cross-sectional in Metabolic syndrome and 10-year cardiovascular disease risk. Metabolic syndrome-related indicators (abdominal obesity, hypertension, hypertriglyceridemia, reduced HDL-C) vs. Normal waist circumference, blood pressure, triglyceride, and HDL-C levels was evaluated on 10-year risk of cardiovascular disease assessed by the Framingham Heart Study tool (low ≤10%, medium 11-20%, high >20%) (OR 2.07 (abdominal obesity); OR 24.52 (hypertension); OR 1.86 (hypertriglyceridemia for medium risk)).
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