Key result
Advanced cardiovascular signal processing enables quantitative, noninvasive assessment of hemodynamic regulation and electrical stability.
Why the study?
Beat-to-beat fluctuations in cardiovascular variables such as heart rate, arterial blood pressure, stroke volume, and electrocardiographic complex shape have traditionally been ignored or treated as noise to be averaged out, despite reflecting dynamic cardiovascular regulatory responses.
Modern signal processing of beat-to-beat cardiovascular fluctuations offers a quantitative, noninvasive or minimally invasive approach to assess hemodynamic regulation and cardiac electrical stability.
Cardiovascular variables such as heart rate, arterial blood pressure, stroke volume and the shape of electrocardiographic complexes all fluctuate on a beat to beat basis. These fluctuations have traditionally been ignored or, at best, treated as noise to be averaged out. The variability in cardiovascular signals reflects the homeodynamic interplay between perturbations to cardiovascular function and the dynamic response of the cardiovascular regulatory systems. Modern signal processing techniques provide a means of analyzing beat to beat fluctuations in cardiovascular signals, so as to permit a quantitative, noninvasive or minimally invasive method of assessing closed loop hemodynamic regulation and cardiac electrical stability. This method promises to provide a new approach to the clinical diagnosis and management of alterations in cardiovascular regulation and stability.
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Appel et al. (1989) conducted a review in Alterations in cardiovascular regulation and stability. Modern signal processing techniques for beat-to-beat cardiovascular variability analysis was evaluated. Modern signal processing of beat-to-beat cardiovascular fluctuations offers a quantitative, noninvasive method to assess hemodynamic regulation and cardiac electrical stability.
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