Key result
Exercise bouts can trigger cardiac troponin elevations in healthy individuals with uncertain clinical significance.
Why the study?
Elevations in cardiac troponin consistent with cardiac damage have been documented after exercise in apparently healthy individuals, and the prevalence, mechanisms, and clinical significance of exercise-induced cTn release remain incompletely understood.
This review summarizes the biochemistry, prevalence, potential mechanisms, and clinical management of cardiac troponin elevations observed in apparently healthy individuals following exercise.
Regular physical exercise is recommended for the primary prevention of cardiovascular disease. Although the high prevalence of physical inactivity remains a formidable public health issue, participation in exercise programs and recreational sporting events, such as marathons and triathlons, is on the rise. Although regular exercise training reduces cardiovascular disease risk, recent studies have documented elevations in cardiac troponin (cTn) consistent with cardiac damage after bouts of exercise in apparently healthy individuals. At present, the prevalence, mechanism(s), and clinical significance of exercise-induced cTn release remains incompletely understood. This paper will review the biochemistry, prevalence, potential mechanisms, and management of patients with exercise-induced cTn elevations.
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Shave et al. (2010) conducted a review in Exercise-induced cardiac troponin elevation. Physical exercise was evaluated on Cardiac troponin elevation. Bouts of physical exercise can cause cardiac troponin elevations in apparently healthy individuals, though the prevalence, mechanisms, and clinical significance remain incompletely understood.
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