The ART Control Framework: The CORG Equation as a General Control Problem

This paper states a general control framework for assisted reproductive technologies (ART), generalized from the governed synthetic genetic pool program of the Clinical Outcomes Research Group (CORG). The framework specifies any ART modality as an operator on reproduction, defined by an insertion point in the generational step and an action at that point, and poses the control question in three ordered parts: whether an admissible governance policy exists under which the controlled trajectory satisfies preservation constraints set against a measured drift floor, what fraction of the intended benefit of the modality such a policy retains, and which verdict follows where no operating policy exists. Eight modalities are mapped to their operators and graded by the strength of the published evidence that touches them, from established instance to established analog to no verdict by construction. Five verdict classes are defined (preserve, monitor, cap, restrict, no verdict) under a common evidence standard of frozen criteria, measured null distributions, and published failures. Two extensions required before the framework can process content and time operators are specified with their validation burdens and marked proposed. The framework governs models, not people: its verdicts are conditional statements about synthetic trajectories under stated assumptions, and the full text states its boundary in full, including the application claims the record does not support. The record metadata is public; the full text is restricted and available on request to the record owner.