Introduction: Posttraumatic stress disorder (PTSD) is a prevalent mental health condition that may develop following direct or indirect exposure to traumatic events. Psychoeducation offers a low-cost and accessible entry point to care. This review aimed to evaluate the effects of psychoeducation for PTSD and identify the conditions and delivery formats associated with greater effectiveness.Methods: We conducted a systematic review of randomized controlled trials (RCTs) evaluating psychoeducational interventions for PTSD in adults. Searches were performed in PubMed, ScienceDirect, Web of Science, PTSDpubs, and Cochrane databases, covering 1 January 2000 to 30 April 2024 with an additional targeted search for PTSD Coach trials conducted in July and August 2026. Eligible studies included adult participants and assessed psychoeducation delivered as either a stand-alone or primary component. Findings were synthesized narratively.Results: Twenty-six RCTs with a total of 3,304 participants met the inclusion criteria. Psychoeducational interventions varied substantially in format, duration, and delivery.Discussion: Nine trials demonstrated significant reductions in PTSD symptoms attributable to psychoeducation (one preventive intervention and eight post-diagnosis). All trials showing significant between-group effects used digital delivery, and most included form of human guidance. However, overall treatment effects were inconsistent across studies, and the methodological quality of the evidence was limited, with several positive trials presenting some concerns or a high risk of bias. Several trials also reported improvements in outcomes such as perceived stress, anxiety, stigma, and help-seeking intentions.Conclusion: Psychoeducation alone is insufficient as a stand-alone treatment for PTSD but remains a valuable component of stepped-care approaches. Future research should systematically assess outcomes such as stigma reduction and help-seeking behaviours, which are critical for engagement in intensive therapies. Preventive interventions may also benefit from focusing on high-risk populations identified through established risk factors, thereby enhancing trial design and minimizing the inclusion of individuals likely to remit without intervention.Registration: This review was not prospectively registered.
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