Key result
TAVI linked to delayed fatal aortic dissection in two autopsy-confirmed cases.
Why the study?
Aortic dissection may be overlooked as a potential cause of delayed unexplained death occurring days after transcatheter aortic valve implantation (TAVI).
Case Report (n=2)
Case series reveals delayed fatal aortic dissection after transcatheter aortic valve implantation, indicating risks from empirical dual antiplatelet therapy.
We report two cases of autopsy confirmed aortic dissection as a cause of death following trans aortic valve implantation (TAVI). The TAVI procedures were performed via the transapical and transfemoral route, respectively, and death occurred several days after the index procedure and not immediately. This highlights a potential cause of delayed unexplained death days post TAVI and may be overlooked as a potential cause of death in patients undergoing this procedure. This also questions the empirical use of dual antiplatelet therapy following TAVI which could potentially exacerbate this phenomenon.
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Gerber et al. (2010) conducted a case report in Aortic dissection following transcatheter aortic valve implantation (TAVI) (n=2). Transcatheter aortic valve implantation (TAVI) was evaluated on Autopsy-confirmed aortic dissection causing delayed death. Transcatheter aortic valve implantation via transapical or transfemoral routes was followed by delayed fatal autopsy-confirmed aortic dissection in 2 reported cases several days post-procedure.
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