Key result
The Overlapping procedure (n=16) sustained LV volume reduction and elliptical shape at mid-term, unlike sphericity progression after Dor (n=15) and persistent DcT reduction after SAVE (n=12).
Why the study?
The study aimed to investigate mid-term changes in left ventricular geometry and function following Dor, septal anterior ventricular exclusion (SAVE), and Overlapping ventricular remodeling procedures.
Observational (n=43)
Overlapping may favor durable LV geometry post-reconstruction; leaves open optimal technique pending randomized trials.
BACKGROUND: The aim of this study was to investigate the mid-term changes of left ventricular (LV) geometry and function after Dor, septal anterior ventricular exclusion (SAVE), and Overlapping ventricular remodeling procedures. METHODS: Forty-three patients who underwent LV reconstruction for end-stage ischemic heart disease, were divided into three groups, undergoing Dor (n=15), SAVE (n=12), and Overlapping procedures (n=16). Coronary artery bypass grafting and mitral annuloplasty were performed concomitantly when indicated. Left ventricular diastolic and systolic dimensions (LVDd and LVDs), LV end-diastolic and end-systolic volume indexes (LVEDVI and LVESVI), LV ejection fraction (LVEF), deceleration time (DcT), sphericity index (SI), and grade of mitral regurgitation were measured on preoperative and postoperative (immediately and at intermediate-term) echocardiography. RESULTS: In the Dor group, the LVEDVI and LVESVI were significantly reduced immediately after the operation, and increased again at intermediate follow-up. The SI was significantly increased immediately after the operation and increased thereafter in a linear fashion. In the SAVE group, the DcT was significantly reduced immediately after the operation and was not improved in the later stage. In the Overlapping group, the LVEDVI and LVESVI were significantly reduced, and remained as such at intermediate follow-up. The SI was not increased and remained almost unchanged after the operation. CONCLUSION: Progression in LV sphericity after the Dor procedure and persistent reduction of the DcT after the SAVE procedure seem to be procedure-related problems. The Overlapping procedure provided significant LV volume reduction, maintaining the most elliptical LV shape with acceptable early and late mortality.
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Ueno et al. (2007) conducted an observational in End-stage ischemic heart disease (n=43). Overlapping ventricular remodeling procedure vs. Dor procedure (n=15) and SAVE procedure (n=12) was evaluated on Mid-term changes of left ventricular geometry and function (LVEDVI, LVESVI, LVEF, DcT, SI, and mitral regurgitation grade). The Overlapping procedure (n=16) sustained LV volume reduction and elliptical shape at mid-term, unlike sphericity progression after Dor (n=15) and persistent DcT reduction after SAVE (n=12).
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