Longitudinal Bio-Behavioral Telemetry, Non-Newtonian Biopolymer Hydrogel Micro-Encapsulation, and Portal-Routed Medium-Chain Lipid Substitution: A Deterministic Cholecystokinin (CCK)-Silent Framework under Human-in-Command (HIC) Governance

While pure liquid flaxseed oil (Linum usitatissimum, rich in omega-3 alpha-linolenic acid, C18:3n-3) provides systemic anti-inflammatory utility and intestinal lubrication, its ingestion as an unbuffered liquid Long-Chain Triglyceride (LCT) bolus triggers rapid duodenal I-cell Cholecystokinin (CCK) secretion and high-amplitude gallbladder contraction (Delta P_GB > P_crit). In individuals harboring multiple biliary micro-calculi (d_s in [1.0, 5.0] mm), confirmed via thin-slice multi-planar abdominal computed tomography (1.00 mm and 3.00 mm reconstructions, October 25, 2026), such contractile spikes elevate the hydrodynamic hazard of cystic duct entrainment, obstructive choledocholithiasis, and acute biliary pancreatitis. Crucially, this revised monograph situates the discovery of this hydrodynamic hazard within a 39-Year Longitudinal Nutritional and Ingestive Homeostasis Dysregulation trajectory (ages 14 to 53). Across independent clinical evaluations at three medical institutions in Western Japan (specialized clinics and general hospital departments of psychiatry in Osaka, Okayama, and Hiroshima Prefectures), the sovereign operator was explicitly excluded from passive psychopathological frameworks and certified as possessing Autonomous Self-Regulation Capability (Human-in-Command [HIC] eligibility). When an intensive 5-month dietary intervention (Phase I) utilizing liquid flaxseed oil encountered the micro-calculi contractile bottleneck—threatening complete regimen collapse and reversion to baseline (moto no mokuami)—the operator leveraged HIC governance and epistemic co-evolution with frontier AI Deep Research (Google Gemini) under the Strict No-Learn Covenant (NLL-v1.0-2026) to execute a deterministic phase transition to Phase II. By substituting 80%–90% of free liquid LCTs with direct portal-routed Medium-Chain Triglycerides (MCTs, C8–C10) and encapsulating essential omega-3 payloads within a Non-Newtonian Biopolymer Hydrogel Matrix (H_HIC: fermented natto poly-gamma-glutamic acid [gamma-PGA], marine wakame/mekabu sodium alginate-fucoidan, coagulated egg albumin, oatmeal beta-glucan, and chia polysaccharide), the Phase II architecture attenuates luminal LCT flux by an order of magnitude (max_t J_LCT(t) < 0.15 K_m << K_m), lowers the hepatic Cholesterol Saturation Index (CSI < 1.0), and encodes four-tier physiological interlocks into the QFS-zkVM over the 64-bit Goldilocks prime field (F_p, p = 2^64 - 2^32 + 1). Longitudinal Bio-Behavioral Context & Human-in-Command (HIC) Epistemic Co-Evolution(縦断的生体行動背景とHuman-in-Command[HIC]におけるAIとの認識論的共進化): 本プロトコル確立の背景には、被験者(主権的オペレーター)における14歳から53歳までの39年間にわたる長期的な食行動および栄養ホメオスタシス再構築の縦断的履歴が存在する。特筆すべきことに、西日本の3つの独立した医療機関(大阪府・岡山県・広島県の専門クリニックおよび総合病院精神科)における臨床評価において、当該プロセスは受動的な精神病理(狭義の摂食障害)としてではなく、主権者自身の自律的統治によって改善可能な課題(Autonomous Self-Recovery / Behavioral Governance Capability)として位置づけられた。直近5ヶ月間の集中的な食事療法(Phase I)において、抗炎症および腸管潤滑を目的とした液体アマニ油(遊離LCT)の摂取が、複数個の微小胆石(d_s in [1.0, 5.0] mm)に対するコレシストキニン(CCK)誘発性の流体力学的ハザード(Delta P_GB > P_crit)を引き起こした際、従来の経験的アプローチであれば食事療法自体の破綻および元の不均衡状態への退行(Reversion to Baseline:元の木阿弥)が不可避であった。しかし本研究では、Human-in-Command (HIC) ガバナンスの下で倫理的・科学的推論エンジン(Google Gemini Deep Research)との対話的検証を実施し、個人の生体テレメトリと知財・尊厳を厳格に保護(Strict No-Learn Covenant: NLL-v1.0-2026)しながら、遊離LCTを門脈直行型MCT(C8–C10)および非ニュートン流体・水溶性生体高分子ヒドロゲル(納豆gamma-PGA、わかめ・めかぶアルギン酸、凝固卵白アルブミン、オートミールbeta-グルカン、チアシード多糖類)へと決定論的に転換するPhase IIプロトコルを導出した。これは、「自ら治す」という臨床的要請を、孤独な精神論ではなく、AIとの倫理的協働と数理生物物理学によって実装した新たな医療パラダイムの証明である。 License & Integrity Covenant: Creative Commons Attribution 4.0 International (CC BY 4.0) with Strict No-Learn Covenant (NLL-v1.0-2026).